陈康富，北京理工大学准聘教授，博士生导师

研究方向

微流控生物芯片及微全分析系统开发（微流控芯片设计及制造，磁控高通量细胞分选，微纳加工工艺）

基于微流控技术的单细胞组学（单细胞操作，高灵敏度转录组及蛋白组分析）

精准药物递送（跨血脑屏障纳米药物输运，神经电极植入损伤的纳米药物调控，可植入型生物传感器）

教育背景

2013.08—2018.12 佛罗里达大学 机械工程 博士 导师：Z. Hugh Fan 杰出教授

2009.08—2013.06 中国科学技术大学 理论与应用力学 本科 学术导师：杨基铭教授

学术经历

2023.07—至今 西北大学 生物医学工程系 博士后 导师: Shana Kelley 院士

2020.01—2023.07 多伦多大学 药学院 博士后 导师: Shana Kelley 院士

2019.01—2019.10 佛罗里达大学 机械与航空工程系 博士后 导师：Z. Hugh Fan 杰出教授

代表性论文

1. K. Chen, H. Yang, and R. Cai, “Microfluidics for Nanomedicine Delivery” ACS Biomaterials Science & Engineering, 2025 11 (2), 774-783 (中科院分区：2 区，IF：5.14)

2. J. Zhan, F. Wang, Y. Li, J. Li, S. Xiang, Y. Yang, K. Chen*, H. Yang*, and R. Cai*, “A triple signal amplification strategy for accurate and ultrasensitive miRNA-21 detection.” Analytical Chemistry 96, no. 36 (2024): 14464-14470. (中科院分区：1 区，IF：6.7)

3. J. Amontree, K. Chen*, J. Varillas, Z.H. Fan*, “A Capillary-Force-Driven, Single-Cell Transfer Method for Studying Rare Cells.” Bioengineering, 11(6), 542. (中科院分区： 3 区，IF：3.8)

4. K. Chen, B. TV Duong, S. Ahmed, P. Dhavarasa, Z. Wang, M. Labib, C. Flynn, J. Xu, Y. Zhang, H. Wang,

X. Yang, Y. Ma, S.O. Kelley, “A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles.” Nature Communications, 14.1 (2023): 5576. （中科院分区： 1 区，IF： 17.7）

5. K. Chen, and Z. Wang, “Micro-Magnetofluidic System for Rare Cell Analysis: From Principle to Translation”

Chemosensors, 2023, 11, no. 6: 335. (中科院分区： 3 区， IF：4.2)

6. K. Chen, and Z. Wang. “A Micropillar Array Based Microfluidic Device for Rare Cell Detection and Single- Cell Proteomics” Methods and Protocols 6 (5), 80 (中科院分区： 未录， IF：2.4)

7. Y. Ma1, K. Chen1, F. Xia, R. Atwal, H. Wang, S. Ahmed, L. Cardarelli, I. Liu, B. Duong, Z. Wang, J. Wells,

S.S. Sidhu, S.O. Kelley, “Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture”,

ACS Nano, 15, no. 12 (2021): 19202-19210. （中科院分区： 1 区，IF：18.0）

8. K. Chen, J. Amontree, J. Varillas, J. Zhang, T.J. George, Z. Hugh Fan. "Incorporation of lateral microfiltration with immunoaffinity for enhancing the capture efficiency of rare cells." Scientific reports 10, no. 1 (2020): 1-

12. （中科院分区：3 区，IF：4.996）

9. K. Chen, P. Dopico, J. Varillas, J. Zhang, T.J. George, Z.H. Fan, “Integration of Lateral Filter Arrays with Immunoaffinity for Circulating Tumor Cell Isolation”. Angew. Chem. Int. Ed, 58.23 (2019): 7606-7610. (highlighted in the journal cover, top 10% in review performance) （中科院分区： 1 区，IF：16.8）

10. K. Chen, T.Z. Georgiev, W. Sheng, X. Zheng, J.I. Varillas, J. Zhang, Z. Hugh Fan, “Tumor cell capture

patterns around aptamer-immobilized microposts in microfluidic devices”, Biomicrofluidics, 11(5) (2017) 054110 （中科院分区： 3 区，IF：3.258）

授权专利

1.  Z. H. Fan, K. Chen, “Lateral Filter Array Microfluidic Device”, US Patent App. 17/270,167

专著章节

1. K. Chen, T.J. George, Z. Hugh Fan, “Lateral Filter Array Microfluidic Devices for Detecting Circulating Tumor Cells”, Microfluidic Systems for Cancer Diagnosis. New York, NY: Springer US, 2023. 1-13.

2. K. Chen, Z. Hugh Fan, “Lateral Filter Array Microfluidic Devices for Detecting Circulating Tumor Cells”, Microfluidic single cell-based drug assays, Springer Nature (2023)

3. K. Chen, Z. Hugh Fan, “Introduction to Microfluidics”, Circulating Tumor Cells: Isolation and Analysis (2016) 33-50.

4. M. Le, K. Smith, M. Alipanah, K. Chen, J. Lagmay, and Z.H. Fan. "Microfluidics-Enabled Isolation and Single-Cell Analysis of Circulating Tumor Cells." In Single-Cell Assays: Microfluidics, Genomics, and Drug Discovery, pp. 71-93. New York, NY: Springer US, 2023.

会议报告和墙报

1. K. Chen, S.O. Kelley, “A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles.” Annual Aeeting of the American Association for Extracellular Vesicles (AAEV) 2023

2. K. Chen, J. Amontree, Z.H. Fan, “Integration of Lateral Filter Arrays with Antibodies for Isolation of Circulating Tumor Cells”, in Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS 2018); Kaohsiung, Taiwan; Nov. 11-15, 2018

3. K. Chen, T. Georgiev, Z.H. Fan, “Interactions Between Circulating Tumor Cells and Aptamer-Functionalized Microposts in a Flow”, ASME 2017 IMECE, 2017, pp. V007T09A045-V007T09A045

4. K. Chen, J. Varillas, J. Zhang, Z.H. Fan, “Interaction of Cancer Cells with Microposts in a Microfluidic Device Immobilized with Aptamers”, presented at PITTCON CONFERENCE&EXPO 2015, New Orleans, LA, Mar. 6-12, 2015

主持项目

国家海外高层次人才青年项目 2025-2028（主持）

参与项目

National Institutes of Health (NIH), R01, 5R01CA260170-03,

Development of microfluidic enabled CRISPR- Cas9 functional genetic screening technologies for target discovery in cancer immunotherapy

2022-至今 200 万元每年 在研 参与

Chan Zuckerberg Initiative, Location, 320-4011400-30065356-01, Chan-Zuckerburg Biohub Fund

2023-至今 700 万元每年 在研 参与

Nanomedicines Innovation Network, Diagnostics, 2019-T3-02, Development of an integrated chip for exosome analysis in cancer

2019-2023 100 万元每年 结题 参与

荣获奖项

佛罗里达大学机械工程系优秀博士论文奖 2019

Interdisciplinary Microsystems Group (IMG)研究中心优秀学术奖 2019

佛罗里达大学机械工程系研究生优秀研究奖 2018

佛罗里达大学博士生奖学金 2013-2018

学术兼职

国际期刊 Micromachines 主题编辑（影响因子 3.5）

美国生物医学工程学会（Biomedical  Engineering  Society）会员

国际审稿人:PNAS, Angewandte Chemie, Lab on a Chip, Microsystems & Nanoengineering, ACS Sensors 等十余个期刊